Identification of genes involved in interactions between Biomphalaria glabrata and Schistosoma mansoni by suppression subtractive hybridization

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Biomphalysin, a New b Pore-forming Toxin Involved in Biomphalaria glabrata Immune Defense against Schistosoma mansoni

Aerolysins are virulence factors belonging to the b pore-forming toxin (b-PFT) superfamily that are abundantly distributed in bacteria. More rarely, b-PFTs have been described in eukaryotic organisms. Recently, we identified a putative cytolytic protein in the snail, Biomphalaria glabrata, whose primary structural features suggest that it could belong to this b-PFT superfamily. In the present p...

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ژورنال

عنوان ژورنال: Molecular and Biochemical Parasitology

سال: 2007

ISSN: 0166-6851

DOI: 10.1016/j.molbiopara.2006.09.009